A review of five drugs.

    Here are links to Dr. Blevins’ discussion of five drugs to treat hypercortisolism. In each of these podcasts, he reviews the mechanisms of action of these drugs and the results of seminal research studies demonstrating efficacy and side effects. In addition, he shares his insights from employing these drugs to manage patients with hypercortisolism. These five podcasts cover the medications used to treat Cushing’s disease. The first three focus on adrenal biosynthesis inhibitors, including ketoconazole, metyrapone, and osilodrostat (Isturisa). Podcast four reviews the somatostatin receptor ligand pasireotide (Signafor). We conclude the series by reviewing the glucocorticoid receptor modulation by mifepristone (Korlym). 

    Click on each link below to listen. You can also download each podcast using your favorite platforms, including Apple Podcast, Spotify, Amazon Music, Podbean, Google, etc.

    Ketoconazole

    Metyrapone

    Osilodrostat (Isturisa®)

    Pasireotide (Signifor, Signifor LAR)

    Mifepristone (Korlym®)

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