Cushing’s disease and syndrome: The evolving story of hypercortisolism.

How is the emerging knowledge of hypercortisolism influencing how Cushing’s disease and syndrome are understood and affecting the practice and those working on the front lines doing the work and caring for patients?  In this podcast, Michael Evans, Director, Commercial Insights, Learning and Development at Corcept Therapeutics, and Lewis Blevins, M.D., Medical Director of the Californian Center for Pituitary Disorders at UCSF and Pituitary World News Co-founder consider the timeline and evolution of our understanding of the disease.

Follow this timeline as you listen to this highly educational podcast.

The increase in Cushing’s knowledge in the last 20 years, and more dramatically the last 10 years, has had a significant impact and brings a new set of challenges to suspect and recognize these conditions earlier.

© 2021, Pituitary World News. All rights reserved.


  1. Great podcast. I was undiagnosed for about 15 years in the state of Idaho. My main presenting symptoms were blood spots and bruising. This got worse over the years and am now very scarred. I had osteoporatic fractures in my feet and a blood clot 6 weeks after surgery. I have a huge timeline of events, but it wasn’t until 2017 that I was given my first cortisol urine test which came back at 480. I had multiple other test, then I was referred to a pituitary center and had a confirmed pathology pituitary tumor removed. I never had diabetes and my blood pressure got high only in the last couple years prior to treatment. I had edema in my ankles for years. I went to pain management for 7 years. I had gone to multiple doctors including pcp, internal medicine, wound clinic, orthopedics, 5 dermatologists,hospital events such as chest pain- MI, skin infections, blood clot, etc. I am now going through another possible reoccurrence with some normal and abnormal results with suspected more defined hypodensity the the pituitary region again. I may eventually seek out a second opinion. I enjoy your podcasts. It is my goal to advocate for this disease. I got together with a local endo and we did a presentation on Cushing’s at two residency centers.


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